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| Machado,L.H.A.; Palumbo,M.I.P.; Zahn,F.S.; Amorim,R.L.; Farias,M.R.; Werner,J.; Torres Neto,R.; Rodrigues,J.C.; Oliveira,F.C.. |
| With the purpose of shedding light on some doubts in veterinary oncology, the present article intends to compare the results of histopathological and immunohistochemical examinations of unspecific round cell neoplasia, to realize immunophenotyping of canine lymphoma cases, to establish the T or B origin of neoplastic cells, and to determine the degree of proliferation and apoptosis of lymphomas by immunohistochemistry. Of 11 animals presenting immunohistochemical diagnosis of lymphoma, five had been diagnosed as Lymphoma by HE staining of histopathological slides and six had been classified as unspecific round cell neoplasia. All cases submitted to immunohistochemical examination were T-cell lymphomas. There was a positive correlation between cell... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dog; Histopathology; Immunohistochemistry; Round cell neoplasia; Lymphoma. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352015000100032 |
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| Araújo,C.M.T.D.; Pacheco,B.D.; Castro,J.L.C.; Farias,M.R.; Engracia Filho,J.R.. |
| ABSTRACT A female adult dog, with a four-month history of pain and intense pruritus, which eventually resulted in sudden death, was referred for necropsy. Postmortem examination showed thoracic and abdominal serum-sanguineous exudates, multifocal infiltrative renal masses, and similar tumors in the heart. Histopathology revealed midsize infiltrative neoplastic proliferation composed of round cells, sparse cytoplasm, and large hyperchromatic nuclei. Immunohistochemistry revealed CD3+ and CD20-immunoexpression. Histopathological and immunohistochemical findings confirmed the diagnosis of epitheliotropic lymphoma with cardiac and renal metastasis. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Metastasis; Lymphoma; Cutaneous; Canine; Necropsy. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000601461 |
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| Rodigheri,S.M.; Farias,M.R.; Werner,J.; Macedo,T.R.; Ostrowski,M.A.B.. |
| The present report describes a case of Sezary syndrome in a canine with lymphadenomegaly, generalized erithroderma, intense pruritus and disseminated cutaneous nodules and plaques. Biopsy samples were taken from cutaneous nodules and plaques and were diagnosed epitheliotropic T cell cutaneous lymphoma by histology and immunohistochemical stain. Bone marrow cytology confirms leukemia. Diagnosis of Sezary syndrome was achieved through clinical, hematological, citopathological, histopathological and immunohistochemical findings. The patient was treated with Madison-Wisconsin chemotherapy protocol, but died after two mouths of treatment. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cão; Oncologia; Linfoma epiteliotrópico. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352007000500036 |
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